As a part of the back-end fuel cycle, transportation of spent nuclear fuel (SNF) from nuclear power plants (NPPs) to a fuel storage facility is very important in establishing a nuclear fuel cycle. In Korea, the accumulated amount of SNF in the NPP pools is troublesome since the temporary storage facilities at these NPP pools are expected to be full of SNF within ten years. Therefore, Korea cannot help but plan for the construction of an interim storage facility to solve this problem in the near future. Especially, a decision on several factors, such as where the interim storage facility should be located, how many casks a transport ship can carry at a time and how many casks are initially required, affect the configuration of the transportation system. In order to analyze the various possible candidate scenarios, we assumed four cases for the interim storage facility location, three cases for the load capacity that a transport ship can carry and two cases for the total amount of casks used for transportation. First, this study considered the currently accumulated amount of SNF in Korea, and the amount of SNF generated from NPPs until all NPPs are shut down. Then, how much SNF per year must be transported from the NPPs to an interim storage facility was calculated during an assumed transportation period. Second, 24 candidate transportation scenarios were constructed by a combination of the decision factors. To construct viable yearly transportation schedules for the selected 24 scenarios, we created a spreadsheet program named TranScenario, which was developed by using MS EXCEL. TranScenario can help schedulers input shipping routes and allocate transportation casks. Also, TranScenario provides information on the cask distribution in the NPPs and in the interim storage facility automatically, by displaying it in real time according to the shipping routes, cask types and cask numbers that the user generates. Once a yearly transportation schedule is established, TranScenario provides some statistical information, such as the voyage time, the availability of the interim storage facility, the number of transported casks sent from the NPPs, and the number of transported casks received at the interim storage facility. By using this information, users can verify and validate a yearly transportation schedule. In this way, the 24 candidate scenarios could be constructed easily. Finally, these 24 scenarios were compared in terms of their operation cost.