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사회불안장애의 QT Dispersion 연구
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  • 사회불안장애의 QT Dispersion 연구
  • Higher QT Dispersion in Patients with Social Anxiety Disorder
저자명
권영도,임세원,오강섭,Kwon. Young-Do,Lim. Se-Won,Oh. Kang-Seob
간행물명
생물정신의학
권/호정보
2010년|17권 1호|pp.44-48 (5 pages)
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대한생물정신의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Objectives : Social phobia is frequently accompanied with autonomic nerve system symptoms. QT dispersion(QTd) is the maximum inter-lead difference in QT interval, an indicator of the autonomic nerve system(ANS) disparity of the heart itself. The objective of this study is to investigate the ANS disparity, which is measured by QTd, is associated with pathophysiology of social phobia. Methods : This research have compared QT dispersion of 25 physically healthy social phobia outpatients(16 men, 9 women, the average age $35.5{pm}12.9$) and age and sex matched control group of mentally and physically healthy 25 volunteers(16 men, 9 women, the average age $34.83{pm}12.7$). QTd was measured by previously described method. Results : QTd and rate-corrected QTd were significantly higher on the patient group than the control group[QTd(patients vs. controls : $52.60{pm}27.63ms$ vs. $27.53{pm}14.29ms$, p<0.0001), QTd(patients vs. controls : $55.79{pm}27.98ms$ vs. $29.10{pm}14.24ms$, p<0.0001)]. Conclusion : Our study showed that the patients with social phobia have higher QTd than the normal controls. These results suggest that the ANS disparity, which is measured by QTd, is associated with pathophysiology of social phobia.