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뇌 Single Photon Emission Computer Tomography 영상을 이용한 정신분열병 환자의 초기 증상 차이에 대한 연구
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  • 뇌 Single Photon Emission Computer Tomography 영상을 이용한 정신분열병 환자의 초기 증상 차이에 대한 연구
  • Comparative Study on Initial Symptoms Using Single Photon Emission Computer Tomography in Schizophrenia
저자명
이진구,김성민,서영덕,김기성,왕성근,지익성,김정란,Lee. Jin-Gu,Kim. Seong-Min,Seo. Young-Duk,Kim. Ki-Seong,Wang. Seong-Keun,Chee. Ik-Seung,Kim. Jeong-L
간행물명
생물정신의학
권/호정보
2010년|17권 3호|pp.127-135 (9 pages)
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대한생물정신의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Objectives : This study was conducted to compare between hallucination group and delusion group in patient with schizophrenia, using Brain $^{99m}Tc$-ECD PECT. Methods : Among 16 patients with less than 3 schizophrenic episodes, 8 patients whose initial symptom was hallucination were assigned to the hallucination group, and other 8 patients with initial sumptom of delusion were assinged to the hallucination group. All of the patients clinically evaluated using the PANSS and BPRS. Both groups of patients and 8 healthy subjects underwent $^{99m}Tc$-ECD PECT. Results : Score of thinking disturbance subscale of BPRS were significantly lower in the hallucination group than the delusion group. In SPECT analysis, the hallucination group showed significantly increased perfusion in some areas of the right temporal lobe, bilateral limbic lobes and left parietal lobe compared to delusion group. Both group had a reduced rCBF in some areas of the frontal lobe. Conclusion : The hallucniation group, compared with the delusion group, showed significantly increased regional cerebral blood flow in some regions. Therefore, this data suggests that different neural substrates may affect the process of auditory hallucination and delusion.