Performance variations in mixture products such as medicine, food, and chemicals can be caused by their own subcomponents. For instance, a discharge capacity of a lithium-ion battery depends upon the mixture ratio of ethylene, dimethyle, and ethyle-methyle, all of which are subcomponents of an electrolyte solution in the battery. Thus it is crucial to determine tolerances of the mixture ratio in order to maintain the product quality at a desired level. This paper is concerned with the tolerance design of the mixture ratio. In particular, minimizing variance around the mixture ratio is adopted as a decision criterion in this paper. An illustrative example with multiple quality characteristics is given as well.