MC-DS-CDMA is technique where a single data symbol is transmitted at multiple subcarriers which are orthogonal to each other. With this technique, frequency diversity can be achieved. The performance of uplink MC-DS-CDMA systems with the application of MRRC antenna diversity over time variant channels is analyzed. Time variant channels lead to interchannel interference which increases the bit error rate in the receiver. The BER performance of this system over multipath fading environment is evaluated, considering the channel estimation error, carrier frequency offset, and the nonlinear high power amplifier.