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Synthesis of Poly(vinyl alcohol)(PVA) Nanofibers Incorporating Hydroxyapatite Nanoparticles as Future Implant Materials
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  • Synthesis of Poly(vinyl alcohol)(PVA) Nanofibers Incorporating Hydroxyapatite Nanoparticles as Future Implant Materials
  • Synthesis of Poly(vinyl alcohol)(PVA) Nanofibers Incorporating Hydroxyapatite Nanoparticles as Future Implant Materials
저자명
Sheikh. Faheem A.,Barakat. Naseer A.M.,Kanjwal. Muzafar A.,Park. Soo-Jin,Park. Dae-Kwang,Kim. Hak-Yong
간행물명
Macromolecular research
권/호정보
2010년|18권 1호|pp.59-66 (8 pages)
발행정보
한국고분자학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

This study examined the mechanical properties of a disc consisting of electro spun poly(vinyl alcohol) (PVA) nanofibers incorporated with high purity hydroxyapatite (HAp) nanoparticles (NPs) for potential hard tissue engineering applications. As HAp NPs are insoluble in a PVA aqueous solution, electrospinning of a colloidal solution was used instead of the conventional process, which is based on completely miscible solutions. The PYA/HAp colloidal solutions were characterized by dynamic light scattering (DLS) and electrophoratic light scattering (ELS), which indicated a unimodal size distribution and negative zeta potential. The physiochemical characterizations con firmed the production of PVA electro spun nanofibers incorporating HAp NPs. To investigate the bioactivity of the produced nanofiber mats, compacted mats with a disc shape were incubated in stimulated body fluid (SBF) at $37^{circ}C$ for 6 days. SEM indicated that the incorporation of HAp strongly activates the precipitation of the apatite-like materials because the HAp NPs act as seeds that accelerate the crystallization of biological HAp from the utilized SBF.