The roller gear cam can control the rotational follower periodically by attaching several roller on the circumstance of follower shaft and it is widely used in non-backlash and precise actuating mechanism such as index table or ATC of machine tools. For machining the roller gear cam, 5 axis CNC machine tool is used and the geometric principle of CAM mechanism must be adopted to generate the NC-code and to develop the special CAD/CAM software because there is not commercial CAM system to machine the roller gear cam. The maker of the specially developed software in domestic user is generally from Japan or Taiwan. However these softwares do not reflect the post processing technique for finish machining in the module. Also, there is some limitation for further new application of itself and it needs higher costs for further application. In this study, the CAD/CAM software to overcome these problem was developed. And its reliability was verified by applying it in 5-axis CNC machining. Finally, the experimental result conducted in the 5-axis machining show good consistency in the movement of follower along the flute and in its Size.