Researches on the Reynolds number effect on bridge decks have made slow progress due to the complicated nature of the subject. Heretofore, few studies on this topic have been made. In this paper, aerostatic coefficients, Strouhal number ($S_t$), pressure distribution and Reynolds number ($R_e$) of Great Belt East Bridge and Sutong Bridge were investigated based on deterministic vortex method (DVM). In this method, Particle Strength Exchange (PSE) was chosen to implement the simulation of the flow around bluff body and to analyze the micro-mechanism of the aerostatic loading and Reynolds number effect. Compared with the results obtained from wind tunnel tests, reliability of numerical simulation can be proved. Numerical results also showed that the Reynolds number effect on aerostatic coefficients and Strouhal number of the two bridges can not be neglected. In the range of the Reynolds number from $10^5$ to $10^6$, it has great effect on the Strouhal number of Sutong Bridge, while the St is difficult to obtain from wind tunnel tests in this range.