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한방 기능성 입욕제 SP1과 SP2의 항산화, 항노화, 미백효과에 관한 연구
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  • 한방 기능성 입욕제 SP1과 SP2의 항산화, 항노화, 미백효과에 관한 연구
저자명
정보경,박소정,김정수,한승헌,손경우,윤미영,이선경,이상재,김병주,권영규,채한,Jung. Bo-Kyoung,Park. So-Jung,Kim. Jung-Soo,Han. Seung-Heon,Sohn. Kyung-Woo,Yoon. Mi-
간행물명
동의생리병리학회지
권/호정보
2010년|24권 5호|pp.837-842 (6 pages)
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대한동의생리학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The purpose of this study is to develop bathing aids as a strategic products to promote the medical tourism in Sancheong Jirisan Oriental medicinal herbs special district using medicinal herbs produced in Sancheong province, and to verify the effect of the bathing aids in vitro. We investigated the cytotoxicity activity, antioxidant activity, antiaging and whitening effects of Sanchung-PNU 1 (SP1) and Sanchung-PNU 2 (SP2) made with traditional medicinal herbs. The cytotoxicity activity was measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Antioxidant activities were determined by DPPH (1.1-diphenyl-2-picrylhydrazyl) radical scavenging capacity assay. We measured the inhibitory effect against tyrosinase activity to prove the whitening effect, and the inhibitory effect against elastase activity to prove the anti-aging effect. Two proposed prescriptions, SP1 and SP2, showed not significant cytotoxicity but significant (p<0.001) improvement in anti-oxidation, anti-wrinkle, and whitening effects compared to the control group. The result shows that these bathing aids have excellent DPPH radical scavenging effect and significant inhibitory effect against elastase and tyrosinase activity. These findings suggest that these bathing aids have a strong antioxidant, anti-aging, and whitening effect.