- 생강(生薑) 추출물의 위장관 기능개선 및 체온저하 억제효과에 대한 실험적 연구
- ㆍ 저자명
- 김남석,정일국,이창현,Kim. Nam-Seok,Jeong. Il-Kook,Lee. Chang-Hyun
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2010년|24권 6호|pp.996-1003 (8 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
This study was performed to investigate the effect of promoting gastrointestinal function and inhibiting of decreasing body temperature of ginger extract(Zingiber officinale) in rats. In order to elucidate the gastrointestinal function and inhibiting effect of body temperature of native ginger and improved ginger, water extracts of ginger were orally administrated into rats. The results are as follows: The gastrointestinal transit time was significantly decreased in native ginger(7.66hrs) and improved ginger(7.72hrs) extract administrated groups compare to control group(8.44hrs). The mean red faecal weight was increased in native ginger(30.6%) and improved ginger(31.1%) extract administrated groups compare to control group(24.9%) for 24hrs. Inhibiting effect of decreasing body temperature induced by serotonin was increased in native ginger($1.116^{circ}C$) and improved ginger($1.416^{circ}C$) extract administrated groups compare to positive control group($0.384^{circ}C$) during 40 minutes. Gastrin and CGRP immunoreactive density was more strongly expressed in native ginger and improved ginger extract administrated groups compare to control group. Serotonin immunoreactive density was more weakly expressed in native ginger and improved ginger extract administrated groups compare to control group. These results suggest that ginger extracts may enhance physiological activity such as gastrointestinal motility, protection of mucosa and gastric acid secretion in gastrointestinal tracts, and inhibits decreasing body temperature