The purpose of this study was to estimate skin care effect of Miso Facial Rejuvenation Acupuncture with the facial skin photographing system and ultrasonography. 4 Patients who made first visits to Daegu Oriental Hospital of Daegu Hanny University from August 7, 2009 to August 12, 2009 were each given five-times treatments of Miso Facial Rejuvenation Acupunture. The facial skin photography of each participant was checked two times-pretreatment, posttreatment-using the facial skin photographing system and ultrasonography. The squares and counts of 2parts of facial winkles and thickness of masseter muscle were measured for each one. The squares and counts of facial wrinkles were decreased. The thickness of masseter muscle were decreased. On this study, we could evaluate the wrinkle treatment effects and reduction of masseter muscle of Miso Facial Rejuvenation Acupuncture by an objective method. Miso Facial Rejuvenation Acupuncture has notable effect in wrinkle treatment and reduction of masseter muscle. As though we had not wide experience in this treatment, more research is needed.