During the cardiopulmonary resuscitation (CPR), the correct chest compression depth and period are very important to increase the resuscitation possibility. For the feedback of chest compression depth, the depth monitoring device based on the accelerometer is developed and widely used. But this method tends to overestimate the compression depth on the bed. To overcome this limitation, the chest compression depth estimation method using two accelerometers is suggested With the additional accelerometer between the patient and mattress on the bed, the compression of the mattress is also measured and it is used to compensate the overestimation error. The experimental results show that the single accelerometer estimates as 61.4mm for the actual compression depth of 43.6mm on the mattress. The depth estimation with the dual accelerometer was 44.6mm which is close to the actual depth. With the automatic zeroing in every single compression, the integration error for the depth can be reduced. The dual accelerometer method is effective to increase the accuracy of the chest compression depth estimation.