In this paper, a numerical study has been carried out to investigate the influence of jet fan design variables on the performance of a jet fan. In order to achieve an optimum jet fan design and to explain the interactions between the different geometric configurations in the jet fan, three-dimensional computational fluid dynamics and the DOE method have been applied. Several geometric variables, i.e., hub-tip ratio, meridional shape, rotor stagger angle, number of rotor-stator blades and stator geometry, were employed to improve the performance of the jet fan. The objective functions are defined as the exit velocity and total efficiency at the operating condition. Based on the results of computational analyses, the performance of the jet fan was significantly improved. The performance degradations when the jet fan is operated in the reverse direction are also discussed.