Objectives : Yangseng is a traditional healthcare regimen on the promotion of health and prevention of illnesses by means of specific principles and methods for the purpose of living a long and healthy life. The purpose of this study was to investigate the relationship of depression level and Yangseng in rural residents for the promotion of health and prevention of illness. Methods: The subjects of this study were 1205 rural residents who live in Wanju. Cheonbuk. Korea. Beck depression inventory and the Yangseng were assessed by survey personnels. Results: The total score of Yangsaeng was $102.70{pm}14.03$, and the BDI score was $2.80{pm}4.96$. Mild depression group was 5.03%. depression and severe depression group was 3.86%. Normal group in depression showed higher Yangsaeng score. and the high Yangsaeng score group showed lower BDI score. Conclusions : Above results suggest that there are signigicant relations between depression and Yangsaeng. These results could be used for planning the public healthcare programs and Yangseng promoting program based on Korean traditional medicine.