The Ottoman dynasty destroyed the Byzantine Empire by occupying Constantinople established the Ottoman Empire and renamed to Istanbul in 1453. Contrary to Islam, the research about Byzantine architecture have an abundant data. Because of the indifference to Islam, there is need today for this sort of study. Islam believe the Biblical Old Testament, I should like to know what is reason for resemblance of the Christian Aya sopia, what is difference in the floor plan between Islam and Judaism. This research applies to the Courtyard type Mosques of SINAN aesthetically completed the Mosque Architecture as a respected architect in 15th century. This study is to investigate the relationship of Orthodox Eastern Church and Islam Mosque within the limit of Istanbul that access is easy and have Christian religion by substratum culture among the many countries that Islam does by diplomatic relations.