Victory and defeat of the war depends on follow-on logistics support. The spending time of follow-on logistics support at combat area is greatly influenced by the degree of combat intensity. The main purpose of this study is to compose a optimal supply route for operational sustainability of combat unit at combat area using transport vehicles. This study suggests a composition of optimal supply route for follow-on logistics support which considers the degree of combat intensity. A mathematical programming model and a genetic algorithm suggest to minimize the total spending time of follow-on logistics support. The suggested mathematical programming model is verified by using CPLEX 11.1. This study computes supply route, total spending time, total travel distance, and the number of transport vehicle.