Indoor cultivation plots for watermelon plant mostly have salt-accumulation problem because of continuous cropping especially with the heavy applications of chemical fertilizers. Thus, this study was conducted to investigate selected soil properties and watermelon growth condition as affected by the application of different farming practices in the salt-affected soils of greenhouse plots used for continuous watermelon production. Five different practice conditions in the experimental plots were applied, 1) a conventional farming practice (CFP), 2) a nitrogen-phosphorus-potassium (NPK) fertilizer management practice (FMP), and 3) the FMP with different amounts (5, 10, and 15 ton $ha^{-1}$)of fresh rice straw treatments (FMP-RS), for three years of study. As comparing with CFP plots, soil organic matter content gradually increased during the experimental years, whereas it decreased in the FMP only plot. Soil pH was not changed in the CFP and FMP plot, but it declined in the FMP-RS plots; however, it increased again from the third year in the FMP-RS plots with applying 10 and 15 ton $ha^{-1}$ of RS treatments. The concentrations of exchangeable cations, $Ca^{2+}$ and $Mg^{2+}$, except $K^+$, and water-soluble anions, ${NO_3}^-$, $Cl^-$, ${SO_4}^{2-}$ and ${PO_4}^{3-}$, markedly decreased in FMP and FMP-RS plots. In particular, the application of rice straw tended to significantly decrease the ion concentrations, especially most anions, in the first year, but there was no more decrease in the second and third study years. With relation to the ion concentrations, the changes of electrical conductivity (EC) after applying the management practices showed very similar to those of the ion concentrations. In addition, incidence of withered watermelon plant after applying the management practices dramatically declined from approximately 20% in the CFP plot to 3.5% in the FMP-RS plots. Water melon fruit weight was also improved by the management practices, especially FMP-RS. Therefore, the fertilizer and/or fresh rice straw application management practices are beneficial to improve salt-affected soils and watermelon plant growth condition.