A Study on the Immobilization of Biomolecules on Poly(acrylic acid)-grafted MWCNTs Prepared by Radiation-Induced Graft Polymerization

A Study on the Immobilization of Biomolecules on Poly(acrylic acid)-grafted MWCNTs Prepared by Radiation-Induced Graft Polymerization
A Study on the Immobilization of Biomolecules on Poly(acrylic acid)-grafted MWCNTs Prepared by Radiation-Induced Graft Polymerization

ㆍ 저자명: 정찬희,이병민,황인태,최재학,노영창,홍성권,Jung. Chan-Hee,Lee. Byoung-Min,Hwang. In-Tae,Choi. Jae-Hak,Nho. Young-Chang,Hong. Sung-Kwon
ㆍ 간행물명: 폴리머
ㆍ 권/호정보: 2010년|34권 2호|pp.150-153 (4 pages)
ㆍ 발행정보: 한국고분자학회
ㆍ 파일정보: 정기간행물|ENG|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

서지반출

영문초록

본 연구에서는 방사선에 의한 그래프트 중합을 이용하여 생체분자가 고정화된 다중벽탄소나노튜브 (MWCNT)를 제조하였다. 생체분자의 고정화를 위하여 MWCNT에 아크릴 산을 그래프트 중합하였다. 열중량분석과 라만 분석을 통하여 MWCNT에 폴리(아크릴 산)이 효과적으로 그래프트 중합되었음을 확인하였다. 폴리(아크릴 산)이 그래프트 된 MWCNT에 DNA와 단백질과 같은 생체분자들을 고정화하였다. X-선 광전자 분광법과 형광분석을 통하여 생체분자들이 성공적으로 MWCNT에 도입되었음이 확인되었다.

기타언어초록

In this research, biomolecule-immobilized multi-walled carbon nanotubes (MWCNTs) were prepared by using radiation-induced graft polymerization. For the immobilization of biomolecules, the surface of MWNCTs was functionalized by radiation-induced graft polymerization of acrylic acid. Based on the results of TGA and Raman spectroscopy it was found that acrylic acid was effectively graft-polymerized on the MWCNTs. Biomolecules such as DNA and proteins were immobilized onto the resultant poly(acrylic acid)-grafted MWCNTs. The results of the X-ray photoelectron spectroscopy and fluorescence microscopy confirmed that the biomoelcules were successfully immobilized on the poly(acrylic acid)-grafted MWCNTs.

키워드

biomolecule multi-walled carbon nanotube poly(acrylic acid)radiation-induced graft polymerization

다운URL