A centrifugal compressor for HFC-134a has been newly designed and developed. Flow analysis using commercial programs was used to evaluate performance and internal flow of the impeller, inlet guide vane and diffuser etc. The purpose of this study is to establish the design theory necessary to the development of HFC-134a centrifugal compressors and to supply basic data related to design by reviewing design values and experimental values through the performance test. The compressor for HFC-134a was also investigated experimentally to check compression performance. The calculated data coincide the test results of compressor. The data obtained in the present study are useful for design of HFC-134a centrifugal compressors.