The structural design of oil tankers and bulk carriers should be performed based on the Common Structural Rules(CSR) which were recently established by the International Association Classification Societies(IACS). At first, in the structural design viewpoint, the scantling and hullweight based on the CSR should be compared with those of existing rules, and then a minimum weight/cost design should be performed by considering the variation of the number of web and the material property. In this study, the optimum web space and material property will be proposed by performing a minimum weight/cost design of a large oil tanker, and the results will be compared with those of existing ship. The longitudinal members are determined by SeaTrust-Holdan developed by the Korean Register of Shipping(KR), and the transverse members are determined by NASTRAN and PULS.