Natural Medicine is a medical system that tries to find the cause and cure of the disease in the nature emphasizing on natural healing power of human body. The most important value of traditional medicine in east Asia lies on the fact that this medicine is a medical culture and natural medicine that was selected by instinct and human nature reflecting the best possible remedy by the wisdom of evolution, and views the living phenomenon based on relation and circulation. This medicine is a natural medicine that tries to recover and promote the natural healing power by vitality and is a system that cumulates various empirical information about unique and complicated life phenomenon as a legacy of evolution in the body and the disease. The understanding of variation and adaptation of human species should be based on thorough knowledge of origin, instinct and nature of human as well as knowledge of survival and adaptation of human and environment based on evolution. And through this insight, the prevention and treatment of modern diseases should be developed. In this regards, traditional medicine in east Asia should be highlighted again as a study on adaptation and harmony of penetrating the cultural history of mind which has led the history of biological body and change of society and culture, and the repository of practical wisdom and knowledge.