In this study, the progressive collapse resisting capacity of mega-frame structures designed in modular concept was investigated using nonlinear static analysis. Four types of mega-frame structures were designed as basic analysis model structures. According to Pushdown analysis results, the mega-frame structure with four corner columns did not satisfy the design guidelines for progressive collapse when one of the first story mega columns was removed. It was also observed that the plastic hinges formed only in the transfer floors. The basic model structure with four mega-columns was redesigned by adding additional floor trusses in the transfer floors, adding moment resisting frames at the perimeter, and adding vertical mega-bracing along the surfaces of the structure. The pushdown analysis results showed that the schemes with additional mega-braces were most effective in increasing progressive collapse resisting capacity of mega-frame buildings.