Effects of enzymatic and atmospheric plasma treatments individually and their combinations on knitted PET fabrics were investigated in terms of hydrophilicity, surface modification and moisture management properties. Cutinase from Humicola Insolens, lipase from Candida SP and atmospheric plasma with air and argon gases were applied to PET fabrics. To evaluate results, moisture management tester (MMT) and scanning electron microscopy (SEM) were utilized. Wicking heights of samples were measured by wicking test method. Improved moisture management properties were observed with environmentally benign processes compared to the untreated ones. Especially combined treatments have given the same or slightly better results than those of conventional alkaline treatments. Fabrics treated with plasma and then followed by enzymatic incubations have significantly improved the wetting time, absorption rates and spreading speed results.