The purpose of this study was to configure a model geared toward predicting factors affecting the sexual behavior of college students and the path of their influence. The standardized path coefficients of factors that might affect their sexual behavior were calculated, and the total effects of the factors were checked when the path of their influence turned out significant. As for the path of the factors affecting the sexual behavior of college students in a firsthand manner, dating exerted a firsthand influence on sexual knowledge. That had the greatest total effect on sexual knowledge, and those with dating experiences had a better sexual knowledge. Sexual knowledge exercised a firsthand influence on sexual attitude, and that had the largest total effect on sexual attitude, as the students who had a better sexual knowledge took a more positive sexual attitude. Sexual roles affected sexual attitude and sexual behavior in a firsthand way, and sexual roles had the biggest total effect on sexual behavior. Androcentric and open sexual attitudes were permissive, distorted and led to more sexual behavior.