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서지반출
Effect of Kombucha Tea on Aflatoxin B1 Induced Acute Hepatotoxicity in Albino Rats-prophylactic and Curative Studies
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  • Effect of Kombucha Tea on Aflatoxin B1 Induced Acute Hepatotoxicity in Albino Rats-prophylactic and Curative Studies
  • Effect of Kombucha Tea on Aflatoxin B1 Induced Acute Hepatotoxicity in Albino Rats-prophylactic and Curative Studies
저자명
Jayabalan. R.,Baskaran. S.,Marimuthu. S.,Swaminathan. K.,Yun. S.E.
간행물명
Journal of the Korean Society for Applied Biological Chemistry
권/호정보
2010년|53권 4호|pp.407-416 (10 pages)
발행정보
한국응용생명화학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Kombucha tea is sugared black tea fermented with a consortium of bacteria and yeasts which forms tea fungus (Medusomyces gisevii) for 14 days. Kombucha tea is claimed to have various beneficial effects on human health but very less scientific evidences are available in the literature. In the present study, the prophylactic and curative effect of black tea (unfermented black tea) and kombucha black tea (KBT) on aflatoxin $B_1$ induced liver damage was studied in male albino rats by analyzing hepatotoxicity markers (aspartate transaminase, alanine transaminase, alkaline phosphatase, gammaglutamyl transpeptidase), lipid peroxidation, reduced glutathione and antioxidant enzymes (glutathione-S-transferase, glutathione peroxidase, glutathione reductase, catalase and superoxide dismutase). Histopathological analysis of liver tissue was also carried out. Results revealed that kombucha tea is more potent in preventing hepatotoxicity than unfermented black tea. The mechanism of hepatoprotection offered by KBT treatment may involve the facilitation of both antioxidant and detoxification processes in the liver.