- 카드뮴(II)-플라보노이드 킬레이트 반응에 관한 연구
- Studies on the Cd(II)-Flavonoid Chelation Reactions
- ㆍ 저자명
- 이정호,신선우,백승화,Lee. Jeong-Ho,Shin. Sun-Woo,Baek. Seung-Hwa
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 2010년|54권 1호|pp.13-21 (9 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The interaction of cadmium (II) ion with quercetin, qurecitrin and (+)-catechin was investigated in aqueous solution at various pH. The flavonoid/cadmium stochiometries for cadmium (II) binding to flavonoid have been determined by UV-visible spectroscopy. 1:1 Cd(II)-Flavonoid complex had a maximum absorbance and showed the bathochromic shift of the long-wavelength band of the UV-vis spectra in the alkaline pH, that occurs upon complexation, is due to a ligand-tometal charge transfer. The optimal concentration of Cd(II)-flavonoid complexes showed that complexation reaction could be classified in the following way: 55.27 ${mu}M$ catechin > 54.72 ${mu}M$ quercetin > 53.52 ${mu}M$ quercitrin at the chelating site level. These results suggest that Cd(II)-flavonoid complex has the optimal condition of chelation in 0.2 M $NH_3$ - 0.2 M $NH_4Cl$ (pH 8.0) solution.