Various air-filter media by using meltblown (MB) and spunbond (SB) nonwovens were structurally designed with different laying methods to obtain the relationship between structure and characteristic of air filters. Air permeability, pore size, filter efficiency and pressure drop of the designed filter media were investigated experimentally. The layer sequences of designed media showed significant factor on filter efficiency and pressure drop. The optimum filter media was determined as two layer structural design composed of calendering SB and MB nonwovens. In addition, a model equation to predict the pressure drop and filter efficiency of air filter media based on nonwovens was developed. The calculated values from the equation showed good agreement with experimental ones.