In this paper, we proposes a method that analyzes the characteristics and patterns of color juxtaposition based on the color wheel used by pointillism painter and an algorithm that generates pointillistic images by applying obtained analysis data. In order to analyze color juxtaposition of pointillism, we extract the stroke colors of real painting and find the most similar probability density functions(PDFs) through applying good-of-fit tests for the probabilistic distribution of stroke colors. By performing the juxtaposition of color based on the found PDFs, we can convert input image to pointillistic image effectively. It can be seen that this study shows reliability in the use of data obtained from actual paintings and that leads to perform a reasonable work.