Modulated liquid jets injected into subsonic cross-flows are empirically studied by using a mechanical liquid jet modulation apparatus. Experimental investigations were conducted using water over a range of cross-flow velocities from 5 m/s to 143 m/s and with modulated liquid jet frequencies from 35.7 Hz to 166.2 Hz and so on. PDPA(phase Doppler particle anemometry) was employed to measure droplet diameter and velocity with various spray cross-sections from Z/d=20 to Z/d=60. The spray structure, penetration depth, SMD(Sauter mean diameter), volume flux and velocity characteristics of modulated liquid jets injected into cross-flows were examined. As oscillation of the periodic pressure that could make liquid jet moved up and down in cross-flow field, the mixing process was facilitated. This phenomenon has the advantage of mixing the spray concentration from the center area to the outer area. Also, a bulk liquid jet puff was detected in the upper field of the liquid jet surface. The modulation effect appears significant in the extent of the spray oscillation. The correlation equations for the liquid jet boundary of the upper and lower regions which related to the Strouhal number have been presented to predict the spray structure under modulation conditions. Because of the modulation frequency, an inclination of averaged SMD for the structured layer was evanescent which contributed to the promotion of the macroscopic spray mixing process. Cross-sectional characteristics of SMD had the same tendency over a range of various modulation frequencies. As the modulation frequency increased, the region of volume flux distribution also increased.