While herbal medicine including mineral herbal medicine mostly provides microelements to the human body thanks to abundant metallic elements, its harmfulness has been raised due to elements of heavy metals. Harmfulness of mineral herbal medicine needs to be analyzed quantitatively as well as qualitatively so that specificity of herbal medicine including mineral herbal medicine can be reflected. Consequently, the following aims should be set up to mineral herbal medicine, REALGAR, standard processing of REALGAR and the standards of processed drugs should be secured. On the basis of the results of this study, the reasonable measures to develop the processing method and the test method for heavy metals were presented. Such measures are expected to give the following results. First, consumers may take food and medicine without anxiety, and food and medicine may be effectively managed, and the national service may be improved, and also safety against heavy metals may be publicized. Second, as the principal ingredients and microelements of mineral herbal medicine are qualitatively analyzed, such results are expected to contribute to the advance of national analytics for herbal medicine.