To compare seed collection and the growth of Anadara subcrenata in Suncheon and Boseong Bays, environmental factors and the growth of larvae and spats were investigated from August 2008 to July 2009 in commercial farming sites in both bays. The variation in water temperature in both bays was similar, but the salinity was lower in Suncheon Bay than in Boseong Bay. The chlorophyll-a content was higher in Suncheon Bay due to the large inflow of freshwater. The density and shell length of A. subcrenata larvae did not differ significantly between the two bays. However, the relative growth of shell height to shell length was significantly higher in Suncheon Bay (P<0.05). The growth of A. subcrenata spats attached to a collector was significantly faster in Suncheon Bay (P<0.05). The spats in Suncheon and Boseong Bays grew to 24.3 and 21.0 mm in shell length, respectively, within 1 year after spawning, and the shell length reached 35.6 and 34.8 mm, respectively, within 2 years of spawning. The initial spats density was higher in Boseong Bay, but the growth of spats was better in Suncheon Bay. The faster growth of A. subcrenata in Suncheon Bay can be explained by the high chlorophyll-a content in this bay. Based on the low survival (%) and slower growth rate of spats in Boseong Bay, the commercial culture density of A. subcrenata in Boseong Bay should be reduced to the optimum level of the carrying capacity.