Purpose: This study was designed to determine whether General Coordinative Manipulation (GCM) Intervention Models have effects on the balanced restoration of asymmetrical muscles in the extremities. Methods: Fifty-nine healthy subjects (1st hypothesis: n=40, 2nd hypothesis: n=19) participated in studies using the two GCM intervention models. Subjects were studied 2 times a week for 3 weeks. Electromyography (EMG) was used to measure muscle activity, and measurements were performed before and after the application of the each intervention model. Results: Hypothesis 1: GCM Intervention, which coordinates flexion types of muscle contractions of the upper extremity and extension types of muscle contractions of the lower extremity (excluding self-care) is effective for treating shows the treatment in efficiency on more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 3 types of 4 body types (Vastus medialis, Gastrocnemius medial of Body type III, p<0.05). GCM body type was classified by the relative tilting of right and left scapulars and iliums into four groups. Hypothesis 2: GCM Intervention, which coordinates flexion types of muscle contractions of the lower extremity and extension types of muscle contractions of the upper extremity (excluding self-care) is effective for treating more than two 2 of 3 muscles (vastus medialis, gastrocnemius medial, and deltoid middle) and the effects affects on more than 2 types of 3 body types (p>0.05).