We have investigated different radial temperature gradient effect on the stability of Taylor-Couette flow. The radius ratio and aspect ratio of the model was 0.825 and 48, respectively. Two heating exchangers were used for generating different temperature gradient along the radial direction. The change of flow regime in the Taylor-Couette flow was studied by increasing the Reynolds number. The results showed that: as Gr is increased in helical vortex flow regime, the vortices with the same direction of convection flow increased in size, and the vortex moving velocity also increased. It is also shown that the presence of temperature gradient obviously increased the flow instability when the Richardson number is larger than 0.0045.