다엽콜리메이터, 겐트리회전, 선량율 등에서 형성되는 플루언스 맵을 이용하여 환자 맞춤형 치료 선량검증이 가능한지 알아보았다. 플루언스 맵은 2D 배열 검출기로 측정하였고, 동일 치료계획을 팬톰 내에서 이온전리함, 필름, 유리선량계 등을 이용하여 측정 비교하였다. 목표점에서 체적감마인자(volume gamma index, 3%, 3 mm)기준에 통과율은 $85.22%{pm}1.7$(RT_target), $89.96%{pm}2.15$였고, G4는 $95.14%{pm}1.18$이었다. 선량 전달 오차는 선량이 급격히 변화는 영역(G1, G2, G3)과 주요장기(G4)에서 각각 $11.72%{pm}0.531$, $-11.47%{pm}0.991$, $7.81%{pm}0.857$, $-4.14%{pm}0.761$이었다. 이온전리함 측정값의 상대오차는 각각 평균 $-1.02%{pm}0.222$ (Rt_target), $0.96%{pm}0.294$ (Lt_target)이었다. 필름의 감마인자(3%, 3 mm) 기준 평균 통과율은 $92.59%{pm}3.312$이었다. 유리선량계 상대 오차는 8.3% (G1), -5.4% (G2), 7.2% (G3), 6.1% (G4)이었다. 체적변조회전방사선 치료(VMAT)시 실시간 플루언스 맵 측정을 통한 실시간 환자 맞춤형 선량 검증이 가능할 것으로 사료되었다.
The purpose of this was to investigate the measurement of fluence dose map for the specific patient quality assurance. The measurement of fluence map was performed using 2D matrixx detector. The absorbed dose was measured by a glass detector, Gafchromic film and ion chamber in Hybrid Optimized VMAT Phantom (HOVP). For 2D Matrixx, the results of comparison were average passing rate $85.22%{pm}1.7$ (RT_Target), $89.96%{pm}2.15$ (LT_Target) and $95.14%{pm}1.18$ (G4). The dose difference was $11.72%{pm}0.531$, $-11.47%{pm}0.991$, $7.81%{pm}0.857$, $-4.14%{pm}0.761$ at the G1, G2, G3, G4. In HOVP, the results of comparison for film were average passing rate (3%, 3 mm) $93.64%{pm}3.87$, $90.82%{pm}0.99$. We were measured an absolute dose in steep gradient area G1, G2, G3, G4 using the glass detector. The difference between the measurement and calculation are 8.3% (G1), -5.4% (G2), 6.1% (G3), 7.2% (G4). The using an Ion-chamber were an average relative dose error $-1.02%{pm}0.222$ (Rt_target), $0.96%{pm}0.294$ (Lt_target). Though we need a more study using a transmission detector. However, a measurement of real-time fluence map will be predicting a dose for real-time specific patient quality assurance in volume modulated arc therapy.
