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Outcomes of small for gestational age micropremies depending on how young or how small they are
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  • Outcomes of small for gestational age micropremies depending on how young or how small they are
  • Outcomes of small for gestational age micropremies depending on how young or how small they are
저자명
Yu. Hee-Joon,Kim. Eun-Sun,Kim. Jin-Kyu,Yoo. Hye-Soo,Ahn. So-Yoon,Chang. Yun-Sil,Park. Won-Soon
간행물명
Korean journal of pediatrics
권/호정보
2011년|54권 6호|pp.246-252 (7 pages)
발행정보
대한소아과학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Purpose: The outcomes of small for gestational age (SGA) infants especially in extremely low birth weight infants (ELBWIs) are controversial. This study evaluated the mortality and morbidity of ELBWIs, focusing on whether or not they were also SGA. Methods: The medical records of 415 ELBWIs (birth weight<1,000 g), who were inborn and admitted to the Samsung Medical Center neonatal intensive care unit from January 2000 to December 2008, were reviewed retrospectively. Mortality and morbidities were compared by body size groups: very SGA (VSGA), birth weight ${leq}$3rd percentile; SGA, 3rd to 10th percentile; and appropriate for gestational age (AGA) infants, >10th percentile for gestational age. For gestational subgroup analysis, groups were divided into infants with gestational age ${leq}24^{+6}$ weeks (subgroup I), $25^{+0}$ to $26^{+6}$ weeks (subgroup II), and ${geq}27^{+0}$ weeks (subgroup III) Results: Gestational age was $29^{+2}{pm}2^{+6}$ weeks in the VSGA infants (n=49), $27^{+5}{pm}2^{+2}$weeks in the SGA infants (n=45), and $25^{+4}{pm}1^{+4}$ weeks in AGA infants (n=321). Birth weight was $692{pm}186.6$ g, $768{pm}132.9$ g, and $780{pm}142.5$ g in the VSGA, SGA, and AGA groups, respectively. Cesarean section rate and maternal pregnancy-induced hypertension were more common in the VSGA and SGA than in AGA pregnancies. However, chorioamnionitis was more common in the AGA group. The mortalities of the lowest gestational group (subgroup I), and also of the lower gestational group (subgroup I+II) were significantly higher in the VSGA group than the SGA or AGA groups (P=0.020 and P=0.012, respectively). VSGA and SGA infants showed lower incidence in respiratory distress syndrome, ductal ligation, bronchopulmonary dysplasia, intraventricular hemorrhage than AGA group did. However, by multiple logistic regression analysis of each gestational subgroup, the differences were not significant. Conclusion: Of ELBWIs, extremely SGA in the lower gestational subgroups, had an impact on mortality, which may provide information useful for prenatal counseling.