Purpose: The objective of this study is to investigate the knowledge and attitude on the contraception and induced abortion in female high school students for providing the fundamental data in developing a practical sexuality education program for the healthy conception and childbirth in female high school students who are in the child-bearing age. Also, this study provides some foundational data for developing prevention education, counsel, and nursing intervention programs. Methods: Data were collected from 270 high school girls by self-report questionnaires from August 1, to September 31, 2010. Data was analyzed by percentage and Pearson correlation coefficient using SPSS/WIN 17.0. Results: The correct rate of contraception and induced abortion were 43.3% and 48.8% respectively. Participants had a moderate attitude toward contraception and a permissive attitude toward induced abortion. Participants who had high score and home sex education were higher correct rate than any other. Conclusion: This study indicates that efforts should be made to provide education on contraception and induced abortion to high school girls to increase awareness. Also, educational programs should be designed to improve knowledge as well as promote a more positive attitude toward contraception and induced abortion.