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Antioxidant Activity and Irritation Test of Extracts Obtained from Angelica dahurica
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  • Antioxidant Activity and Irritation Test of Extracts Obtained from Angelica dahurica
  • Antioxidant Activity and Irritation Test of Extracts Obtained from Angelica dahurica
저자명
Lee. Yang-Suk,Kim. Nam-Woo
간행물명
Journal of food science and nutrition
권/호정보
2011년|16권 1호|pp.8-11 (4 pages)
발행정보
한국식품영양과학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In this study, we assessed the free radical scavenging and xanthine oxidase inhibitory activities of extracts isolated from the dried roots and stems (including leaves) of Angelica dahurica. The irritation response from these extracts was also assessed to determine potential cosmetic use. Both sources of A. dahurica extracts exhibited radical scavenging properties to different extents. The free radical scavenging potency ($EC_{50}$) of the stems (including leaves) of A. dahurica was 243.33 ${mu}g/mL$, which is significantly lower (p<0.01) than that observed of the roots (1,161.79 ${mu}g/mL$). The inhibition values ($EC_{50}$) of xanthine oxidase were as follows: 435.19 ${mu}g/mL$ (roots) and 434.66 ${mu}g/mL$ (stems). We noted no significant differences between the two plant parts with regard to ability to inhibit xanthine oxidase activity. After the application of A. dahurica extracts to rabbits for skin and eye irritation tests, no negative effects were observed; therefore, the extracts are considered to be non-irritating to the skin and eye.