The present study aims at investigating the effect of the fluid-structure interaction on the aerodynamic performances in the turbo blower. The design specifications of the reference model driven by 400kW power were given as 7.43kg/s of mass flow rate, 1.66 of pressure ratio with 12000rpm of impeller rotating speed. Numerical simulation has been performed on the three cases based on the tip clearance between the impeller blade and the shroud. The CFX-turbo for flow fields and ANSYS-mechanical for structure domain were applied to solve the present FSI problems inside the turbo blower. Through the numerical results, the performances corrected by the FSI effects were proposed for the more reliable predictions.