The mining of imitated manganese noodles in 1000 m of seawater is planned for 2012. Thus, it is necessary to prepare the lifting pipes to be used for the test. Because of storage and expense constraints, flexible and economic HDPE pipe is being considered, making it necessary to test the structural safety. Material, pressure-chamber tests and finite element analysis of HDPE pipe for the 1000-m depth were performed. The tangential stiffness of HDPE was obtained through tension and three-point bending material tests and used for a structural analysis. FEA results show that the current sample pipe segment is safe for 1000 m of water pressure, and the stress result is also within the safe value. From the current results, the HDPE pipe seems to be acceptable only for the currently suggested constraints. However, more numerical and pressure tests need to be considered by applying additional physical conditions such as gravitational and hydrodynamic loads, external and internal fluid pressure, axial force induced ship motion, and heavy pump pressure to determine future usage.