In this study a novel cogeneration system driven by low-temperature sources at a temperature level below $190^{circ}C$ is investigated by first and second laws of thermodynamics. The system consists of Organic Rankine Cycle(ORC) and an additional heat generation as a parallel circuit. Seven working fluids of R143a, R22, R134a, R152a, $iC_4H_{10}$(isobutane), $C_4H_{10}$(butane), and R123a are considered in this work. Maximum mass flow rate of a working fluid relative to that of the source fluid and optimum turbine inlet pressure are considered to extract maximum power from the source. Results show that due to a combined heat and power generation, both the efficiencies by first and second laws can be significantly increased in comparison to a power generation, however, the second law efficiency is more resonable in the investigation of cogeneration systems. Results also show that the working fluid for the maximum system efficiency depends on the source temperature.