The frame for automotive assembly can be deformed and remained on the residual stress due to high temperature thermal attacks when in welding. The frame deformation can be made to problems when in assembly with body and the residual stress can affect the negative effect on durability performance of the automobile. In order to analyze the frame deformation, the simplified test frame which had the similar shape (form) of the real automotive frame was fabricated. The contactless optical 3D scanner was used for the shape difference measurement of the frame between before and after the welding. The FE-model of the test frame was composed and the heat transfer and thermal stress simulation were performed. The simulated results were compared with the measured results for the reference of the frame design. The deformation shape of the frame by simulation was in good agreement with that by the experimental measurement.