The growing interest in nanotechnology has resulted in increasing concern and a number of published environmental and workplace measurements for assessing occupational exposure to engineered nanomaterials. However, the amount of previous exposure data remains limited. Furthermore the data available was collected with extensive variation in terms of exposure measurement strategy, which limits the ability to pool the data in the future. In response, this paper reviewed several pertinent issues related to exposure measurement strategy to suggest a harmonized measurement strategy which would make exposure data more useful in the future, e.g. correlation between exposure metrics, relationship between activity and exposure, task-based or shift-based assessment, background concentration, limitation of personal exposure monitoring and other determinants of exposure/modeling. An improved sampling strategy for nanomaterial exposure assessment should be considered in order to maximize the use of the data from various real time monitoring instruments.