Purpose: The purpose of this study was to provide the information of renal disease patients and to provide evidence the physical therapy recipient of renal disease patients. The reviews suggest that renal disease patients are physical inactivity situation, increase on cardiopulmonary risk factor, developed complication disease, increased psychosocial factor like depress and anxiety, decreased Quality of life because their disease effects. Thus. exercise program seems to have beneficial effect on physiologic and psychosocial functioning, Quality of life. It is expected that this study will consider rehabilitation program for internal medicine patients and should be consider as availability of therapeutic exercise program on understanding renal disease in physical therapy.