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Analgesic and anti-inflammatory activities of $Alocasia$ $indica$ ($Roxb.$) $Schott$
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  • Analgesic and anti-inflammatory activities of $Alocasia$ $indica$ ($Roxb.$) $Schott$
저자명
Rahman. Md. Atiqur,Solaiman. Md.,Haque. Md. Ekramul,Das. A.K.
간행물명
Oriental pharmacy and experimental medicine : OPEM
권/호정보
2011년|11권 3호|pp.143-146 (4 pages)
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The ethanol extract of the dried rhizome of Alocasia indica (Roxb.) Schott. (Family - Araceae) was investigated for its possible analgesic and anti-inflammatory activities in animal models. The extract showed significant ($P$ <0.001) writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 300 and 600 mg/kg of body weight comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. Moreover, when given orally to rats at dose of 300 and 600 mg/kg of body weight, the extract showed a significant ($P$ <0.001) anti-inflammatory activity against carrageenin induced paw edema in rats which was comparable to the standard drug aspirin at the dose of 150 mg/kg of body weight. The overall results tend to suggest the analgesic and anti-inflammatory activities of the crude ethanolic extract of dried rhizome of $Alocasia$ $indica$ ($Roxb.$) $Schott$. The obtained results provide a support for the use of this plant in traditional medicine and its further investigation.