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Neuropharmacological assessment of $Curcuma$ $caesia$ rhizome in experimental animal models
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  • Neuropharmacological assessment of $Curcuma$ $caesia$ rhizome in experimental animal models
  • Neuropharmacological assessment of $Curcuma$ $caesia$ rhizome in experimental animal models
저자명
Karmakar. Indrajit,Saha. Pathik,Sarkar. Nilanjan,Bhattacharya. Sanjib,Haldar. Pallab K.
간행물명
Oriental pharmacy and experimental medicine : OPEM
권/호정보
2011년|11권 4호|pp.251-255 (5 pages)
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경희한의학연구센터
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

$Curcuma$ $caesia$ Roxb. (Zingiberaceae), called black turmeric in English, is a perennial herb found throughout the Himalayan region, North-East and Central India. The plant has been traditionally used in India for several medicinal purposes. The present study was carried out to evaluate the methanol extract of $C.$ $caesia$ rhizome (MECC) for some neuropharmacological activities in experimental animal models. MECC (at 50 and 100 mg/kg body weight) was evaluated for analgesic activity by acetic acid-induced writhing and tail flick tests. Locomotor activity was measured by means of an actophotometer. Anticonvulsant property was assessed against pentylenetetrazol-induced convulsion in mice and muscle relaxant effect was evaluated by using rota-rod apparatus. The results of the present study revealed remarkable analgesic, locomotor depressant, anticonvulsant and muscle relaxant effects of $C.$ $caesia$ rhizome, demonstrating depressant action on the central nervous system. The outcome of present study can validate certain traditional uses of $C.$ $caesia$ rhizome in India.