Objective: The objective of this study was to evaluate a work of building cleaners using the ergonomic methods. Background: Previous studies about cleaning worker describe typical physical demands of this work. They found that the most significant risk factors associated with the physical work of cleaners are static loads and repetitive movements and high output of force. Method: A head of ergonomics estimation was work analysis(define of combined task, work tool, work time and frequency of combined task) and posture analysis of worker. Results: The results showed that combined task of building cleaners was classification sweeping, mopping(wet), mopping(oil), moving barrels/carts, dumping trash bags, scrubbing, arrangement of cleaning tool, arrangement of circumferential, moving of cleaning tool, and waiting. The work time of combined task such as mopping(wet) and scrubbing indicated high ratio. The posture analysis of building cleaners indicated high value in bending of the head, lower arm, and hands. Conclusion: The findings appear to indicate that building cleaner were related to high risk of work-related musculoskeletal disorders. So, building cleaner would be required an interventional strategy, improvement of cleaning tools and working environment. Application: If ergonomics rule can be integrated into existing cleaning tools and work environments, the risk of occupational injuries will be reduced.