In cell biology area, microscopy enables detecting objects inside cells that are stained or fluorescently tagged. It is disadvantageous for observing these objects because of the noisy characteristics of their environmental surrounding. In this paper, a framework is proposed to increase the throughput and reliability for analysis of these images. First, we apply adaptive beamlet transform to extract edges meaningfully followed by orientation, location, and length in different scales. Then, a post-process is implemented to extend and map them onto original image. Our proposed scheme is compared with Canny edge detector and conventional beamlet transform from four evaluation aspects. It produces better results when experiments are conducted on real images. Much better results for observing internal parts make this framework competitive for analysis of cell images.