This study has examined the effect of music Rope-skipping on body composition and health related blood components of middle school students. The experiment has been performed for 12 weeks, varying the exercise intense depending on preliminary stage, elementary and intermediate stage and conclusion is as follows based on the change in body composition, blood components related to health before and after the experiment. All males and females showed decreased, but there were no statistically different in body fat mass and body fat percentage. Fat-free mass of males showed decreased and females had an increased, but there were no statistically different. Regarding body-mass index of males and females were on the decreased, but there were no statistically different. As for hematocrit of males and females statistically grew by about 4.53%(p<.05). The number of erythrocyte and leukocyte in males and females showed increased, but there were no statistically difference. Concerning hemoglobin of males and females showed a increased(p<.01). The number of thrombocyte of males and females were on the increased, but there were no statistically different. Cholesterol in males and females were on the decreased, but it was not statistically different. Blood glucose of males and females were on the decreased(p<.05).