Objective: The purpose of this study was to investigate the effect of food intake on the Fourier components of radial pulse wave. Methods: Thirty-one healthy male subjects participated in this study. Radial pulse was measured using 3 dimensional pulse imaging system (DMP-3000) before, right after, 40 minutes after, 80 minutes after and 120 minutes after food intake. Fourier transform was performed and the frequency and amplitude of Fourier components were analyzed. Results: 1. The frequency and the amplitude of Fourier components of radial pulse wave increased significantly after food intake. 2. The frequency of Fourier components increased right after food intake and then gradually decreased as time passed, however the amplitude of Fourier components increased and maintained certain levels and patterns throughout the experimental period of 120 minutes. 3. The change ratios of the frequency and the amplitude of Fourier components after food intake varied with the pulse measuring locations. Conclusions: Food intake exerts an influence on radial pulse wave, resulting in increase of frequency and amplitude of Fourier components. The change ratios of the frequency and the amplitude of Fourier components after food intake varied with the pulse measuring locations.