Purpose: This study was to compare the Transtheoretical Model components according to the stage of change in smoking cessation behavior and identify factors associated with preparation to quit smoking among college smokers. Methods: Data were collected from 224 undergraduate students using the self-report questionnaire. The survey variables comprised the stage of change in smoking cessation, self-efficacy, and decisional balance and process of change in smoking cessation. Results: There were significant differences in self-efficacy, cons of smoking, and the process of change according to the stage of change in smoking cessation behavior. Cons of smoking and self liberation were significant factors related to the preparation stage of smoking cessation. Conclusion: Strategies to enhance cons of smoking and self liberation in college smokers will be an important intervention component to prepare and plan smoking cessation in future studies.